Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8

Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8

© 2018 American Chemical Society. To gain a better understanding of the conjugation chemistry taking place at the interface of the capsular polysaccharide repeating units, described herein is the synthesis of two disaccharides. These disaccharides correspond to the connection point of the repeating...

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Main Authors: Satsawat Visansirikul, Stephen A. Kolodziej, Alexei V. Demchenko
Other Authors: University of Missouri-St. Louis
Format: Article
Published: 2020
Subjects:
Chemistry
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/50580
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spelling th-mahidol.505802020-01-27T15:15:29Z Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8 Satsawat Visansirikul Stephen A. Kolodziej Alexei V. Demchenko University of Missouri-St. Louis Mahidol University Bioprocess RandD Chemistry © 2018 American Chemical Society. To gain a better understanding of the conjugation chemistry taking place at the interface of the capsular polysaccharide repeating units, described herein is the synthesis of two disaccharides. These disaccharides correspond to the connection point of the repeating units of capsular polysaccharide S. aureus serotype 5 (CP5) and serotype 8 (CP8). As in our previous syntheses of trisaccharide repeating units, the potential propagation positions are blocked with methyl groups. 2020-01-27T08:15:29Z 2020-01-27T08:15:29Z 2019-01-04 Article Journal of Organic Chemistry. Vol.84, No.1 (2019), 216-227 10.1021/acs.joc.8b02612 15206904 00223263 2-s2.0-85059587313 https://repository.li.mahidol.ac.th/handle/123456789/50580 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85059587313&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Chemistry
spellingShingle Chemistry
Satsawat Visansirikul
Stephen A. Kolodziej
Alexei V. Demchenko
Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
description © 2018 American Chemical Society. To gain a better understanding of the conjugation chemistry taking place at the interface of the capsular polysaccharide repeating units, described herein is the synthesis of two disaccharides. These disaccharides correspond to the connection point of the repeating units of capsular polysaccharide S. aureus serotype 5 (CP5) and serotype 8 (CP8). As in our previous syntheses of trisaccharide repeating units, the potential propagation positions are blocked with methyl groups.
author2 University of Missouri-St. Louis
author_facet University of Missouri-St. Louis
Satsawat Visansirikul
Stephen A. Kolodziej
Alexei V. Demchenko
format Article
author Satsawat Visansirikul
Stephen A. Kolodziej
Alexei V. Demchenko
author_sort Satsawat Visansirikul
title Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
title_short Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
title_full Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
title_fullStr Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
title_full_unstemmed Synthesis of D-FucNAc-D-ManNAcA Disaccharides Based on the Capsular Polysaccharides Staphylococcus aureus Type 5 and 8
title_sort synthesis of d-fucnac-d-mannaca disaccharides based on the capsular polysaccharides staphylococcus aureus type 5 and 8
publishDate 2020
url https://repository.li.mahidol.ac.th/handle/123456789/50580
_version_ 1763488326670614528

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