An immortalized hepatocyte-like cell line (imHC) accommodated complete viral lifecycle, viral persistence form, cccDNA and eventual spreading of a clinically-isolated HBV

• Main Authors: Khanit Sa-Ngiamsuntorn, Piyanoot Thongsri, Yongyut Pewkliang, Adisak Wongkajornsilp, Pattida Kongsomboonchoke, Phichaya Suthivanich, Suparerk Borwornpinyo, Suradej Hongeng
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/51002
• Institution: Mahidol University

© 2019 by the authors. Licensee MDPI, Basel, Switzerland. More than 350 million people worldwide have been persistently infected with the hepatitis B virus (HBV). Chronic HBV infection could advance toward liver cirrhosis and hepatocellular carcinoma. The intervention with prophylactic vaccine and c...