Atovaquone-Proguanil in Combination with Artesunate to Treat Multidrug-Resistant P. falciparum Malaria in Cambodia: An Open-Label Randomized Trial

• Main Authors: Mariusz Wojnarski, Chanthap Lon, Pattaraporn Vanachayangkul, Panita Gosi, Somethy Sok, Agus Rachmat, Dustin Harrison, Catherine M. Berjohn, Michele Spring, Suwanna Chaoratanakawee, Mali Ittiverakul, Nillawan Buathong, Soklyda Chann, Saowaluk Wongarunkochakorn, Andreea Waltmann, Worachet Kuntawunginn, Mark M. Fukuda, Hana Burkly, Vireak Heang, Thay Keang Heng, Nareth Kong, Threechada Boonchan, Bolin Chum, Philip Smith, Andrew Vaughn, Satharath Prom, Jessica Lin, Dysoley Lek, David Saunders
• Other Authors: The University of North Carolina at Chapel Hill
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/51368
• Institution: Mahidol University

© 2019 Published by Oxford University Press on behalf of Infectious Diseases Society of America 2019. Background: Recent artemisinin-combination therapy failures in Cambodia prompted a search for alternatives. Atovaquone-proguanil (AP), a safe, effective treatment for multidrug-resistant Plasmodium...