Antimicrobial-resistant Gram-negative colonization in infants from a neonatal intensive care unit in Thailand
© 2019 The Author(s) Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a...
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Main Authors: | , , , , , |
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Format: | Article |
Published: |
2020
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/51397 |
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Institution: | Mahidol University |
Summary: | © 2019 The Author(s) Antimicrobial-resistant Gram-negative bacteria are a major cause of morbidity and mortality in hospitalized neonates in South and South-East Asia. This study aimed to determine the dynamics of colonization with antimicrobial-resistant Gram-negative bacteria amongst patients in a neonatal intensive care unit (NICU) in Thailand. From 97 enrolled patients, 52% were colonized by an extended-spectrum β-lactamase (ESBL) organism at some point during their stay and 64% were colonized by a carbapenem-resistant organism. Rapid acquisition of ESBL-positive and carbapenem-resistant organisms was found. Once colonized with an antibiotic-resistant organism, patients remained colonized for the remainder of their NICU stay. |
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