miR-144 regulates oxidative stress tolerance of thalassemic erythroid cell via targeting NRF2

• Main Authors: Kanitta Srinoun, Nuankanya Sathirapongsasuti, Kittiphong Paiboonsukwong, Somporn Sretrirutchai, Malai Wongchanchailert, Suthat Fucharoen
• Other Authors: Faculty of Medicine, Prince of Songkia University
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/51438
• Institution: Mahidol University

© 2019, Springer-Verlag GmbH Germany, part of Springer Nature. Thalassemia has a high prevalence in Thailand. Oxidative damage to erythroid cells is known to be one of the major etiologies in thalassemia pathophysiology. Oxidative stress status of thalassemia is potentiated by the heme, nonheme iron...