HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians

• Main Authors: Shih Chi Su, Chun Bing Chen, Wan Chun Chang, Chuang Wei Wang, Wen Lang Fan, Lai Ying Lu, Ryosuke Nakamura, Yoshiro Saito, Mayumi Ueta, Shigeru Kinoshita, Chonlaphat Sukasem, Kittika Yampayon, Pornpimol Kijsanayotin, Nontaya Nakkam, Niwat Saksit, Wichittra Tassaneeyakul, Michiko Aihara, Yu Jr Lin, Chee Jen Chang, Tony Wu, Shuen Iu Hung, Wen Hung Chung
• Other Authors: University of Phayao
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/51938
• Institution: Mahidol University

© 2018 American Society for Clinical Pharmacology and Therapeutics To develop a pre-emptive genetic test that comprises multiple predisposing alleles for the prevention of phenytoin-related severe cutaneous adverse reactions (SCARs), three sets of patients with phenytoin-SCAR and drug-tolerant contr...