Atorvastatin attenuates obese-induced kidney injury and impaired renal organic anion transporter 3 function through inhibition of oxidative stress and inflammation

• Main Authors: Nattavadee Pengrattanachot, Rada Cherngwelling, Krit Jaikumkao, Anchalee Pongchaidecha, Laongdao Thongnak, Myat Theingi Swe, Varanuj Chatsudthipong, Anusorn Lungkaphin
• Other Authors: Mahidol University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/53557

© 2020 Elsevier B.V. An excessive consumption of high-fat diet can lead to the alterations of glucose and lipid metabolism, impaired insulin signaling and increased ectopic lipid accumulation resulting in renal lipotoxicity and subsequent renal dysfunction. Atorvastatin is a lipid-lowering drug in c...