Plasmodium-infected erythrocytes induce secretion of IGFBP7 to form type II rosettes and escape phagocytosis

• Main Authors: Wenn Chyau Lee, Bruce Russell, Radoslaw Mikolaj Sobota, Khairunnisa Ghaffar, Shanshan W. Howland, Zi Xin Wong, Alexander G. Maier, Dominique Dorin-Semblat, Subhra Biswas, Benoit Gamain, Yee Ling Lau, Benoit Malleret, Cindy Chu, François Nosten, Laurent Renia
• Other Authors: A-Star, Singapore Immunology Network
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/53584
• Institution: Mahidol University

© 2020, Lee et al. In malaria, rosetting is described as a phenomenon where an infected erythrocyte (IRBC) is attached to uninfected erythrocytes (URBC). In some studies, rosetting has been associated with malaria pathogenesis. Here, we have identified a new type of rosetting. Using a step-by-step a...