Enhancement of sialylation in rIgG in glyco-engineered Chinese hamster ovary cells

© 2020, Springer Nature B.V. Since about 70% of commercial biopharmaceutical products have been produced in Chinese hamster ovary (CHO) cells, this cell line is undeniably a workhorse for biopharmaceuticals production. Meanwhile, sialic acid terminals were reported to affect anti-inflammatory activi...

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Bibliographic Details
Main Authors: Thi Sam Nguyen, Ryo Misaki, Takao Ohashi, Kazuhito Fujiyama
Other Authors: Osaka University
Format: Article
Published: 2020
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/53600
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Institution: Mahidol University