Mulberry fruit cultivar ‘Chiang Mai’ prevents beta-amyloid toxicity in PC12 neuronal cells and in a Drosophila model of Alzheimer’s disease

• Main Authors: Uthaiwan Suttisansanee, Somsri Charoenkiatkul, Butsara Jongruaysup, Somying Tabtimsri, Dalad Siriwan, Piya Temviriyanukul
• Other Authors: Kasetsart University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/54464
• Institution: Mahidol University

© 2020 by the authors. Alzheimer’s disease (AD) is the most common form of dementia, characterized by chronic neuron loss and cognitive problems. Aggregated amyloid beta (Aβ) peptides, a product of cleaved amyloid precursor protein (APP) by beta-secretase 1 (BACE-1), have been indicated for the prog...