Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Burkina Faso: An open label trial [version 2; peer review: 2 approved]

• Main Authors: Sofia Birgersson, Innocent Valea, Halidou Tinto, Maminata Traore-Coulibaly, Laeticia C. Toe, Richard M. Hoglund, Jean Pierre Van Geertruyden, Stephen A. Ward, Umberto D’Alessandro, Angela Abelö, Joel Tarning
• Other Authors: Universiteit Gent
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/54494
• Institution: Mahidol University

© 2020 Birgersson S et al. Background: Malaria during pregnancy is a major health risk for both the mother and the foetus. Pregnancy has been shown to influence the pharmacokinetics of a number of different antimalarial drugs. This might lead to an under-exposure in these patients which could increa...