Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand
© 2020, Springer Nature Switzerland AG. Background Renal dosage adjustment for patients with reduced kidney function is a common function of clinical pharmacy service. Assessment of pharmacist’s intervention in the aspect of quality and economic impact should be conducted to evaluate the benefit of...
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th-mahidol.545612020-05-05T13:06:10Z Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand Sayamon Sukkha Wipharak Rattanavipanon Benjawan Chamroenwit Malita Sanganurak Surakit Nathisuwan Usa Chaikledkaew Junporn Kongwatcharapong Mahidol University Faculty of Medicine, Siriraj Hospital, Mahidol University Health Professions Medicine Pharmacology, Toxicology and Pharmaceutics © 2020, Springer Nature Switzerland AG. Background Renal dosage adjustment for patients with reduced kidney function is a common function of clinical pharmacy service. Assessment of pharmacist’s intervention in the aspect of quality and economic impact should be conducted to evaluate the benefit of this service. Objective This study aimed to assess the quality and cost saving of clinical pharmacists’ recommendation on renal dosage adjustment among patients with reduced kidney function. Setting Eight medical wards of the Siriraj Hospital, a tertiary-care hospital in Bangkok, Thailand. Method A retrospective study was conducted using medical records and clinical pharmacist’s intervention database. All patients admitted to the study wards whose estimated creatinine clearance were less than 60 mL/min or presented with acute kidney injury on admission during October 2016–December 2017 were included. The targeted medications were antimicrobial agents. Main outcome measure Percentage of the concordance between pharmacists’ recommendation compared to standard dosing references and related cost saving. Results Among 158 patients, pharmacists provided 190 recommendations, including 151 (79.1%) dose reduction, 17 (8.9%) dose increase and 22 (11.5%) recommendations to provide supplemental dose after dialysis. These recommendations were 90.5% consistent with standard references. Physician accepted and complied with 89.5% of pharmacists’ recommendations. Average direct cost saving was €5,114.11 while cost avoidance was €863.47. Conclusion Trained clinical pharmacists were able to provide high-quality recommendation on dosage adjustment in these patients in accordance to standard dosing guidelines. In addition, dosage adjustment also led to a significant direct cost saving and cost avoidance from prevention of adverse drug reactions. 2020-05-05T05:26:13Z 2020-05-05T05:26:13Z 2020-01-01 Article International Journal of Clinical Pharmacy. (2020) 10.1007/s11096-020-01016-1 22107711 22107703 2-s2.0-85082933006 https://repository.li.mahidol.ac.th/handle/123456789/54561 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85082933006&origin=inward |
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Health Professions Medicine Pharmacology, Toxicology and Pharmaceutics Sayamon Sukkha Wipharak Rattanavipanon Benjawan Chamroenwit Malita Sanganurak Surakit Nathisuwan Usa Chaikledkaew Junporn Kongwatcharapong Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
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© 2020, Springer Nature Switzerland AG. Background Renal dosage adjustment for patients with reduced kidney function is a common function of clinical pharmacy service. Assessment of pharmacist’s intervention in the aspect of quality and economic impact should be conducted to evaluate the benefit of this service. Objective This study aimed to assess the quality and cost saving of clinical pharmacists’ recommendation on renal dosage adjustment among patients with reduced kidney function. Setting Eight medical wards of the Siriraj Hospital, a tertiary-care hospital in Bangkok, Thailand. Method A retrospective study was conducted using medical records and clinical pharmacist’s intervention database. All patients admitted to the study wards whose estimated creatinine clearance were less than 60 mL/min or presented with acute kidney injury on admission during October 2016–December 2017 were included. The targeted medications were antimicrobial agents. Main outcome measure Percentage of the concordance between pharmacists’ recommendation compared to standard dosing references and related cost saving. Results Among 158 patients, pharmacists provided 190 recommendations, including 151 (79.1%) dose reduction, 17 (8.9%) dose increase and 22 (11.5%) recommendations to provide supplemental dose after dialysis. These recommendations were 90.5% consistent with standard references. Physician accepted and complied with 89.5% of pharmacists’ recommendations. Average direct cost saving was €5,114.11 while cost avoidance was €863.47. Conclusion Trained clinical pharmacists were able to provide high-quality recommendation on dosage adjustment in these patients in accordance to standard dosing guidelines. In addition, dosage adjustment also led to a significant direct cost saving and cost avoidance from prevention of adverse drug reactions. |
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Mahidol University |
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Mahidol University Sayamon Sukkha Wipharak Rattanavipanon Benjawan Chamroenwit Malita Sanganurak Surakit Nathisuwan Usa Chaikledkaew Junporn Kongwatcharapong |
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Article |
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Sayamon Sukkha Wipharak Rattanavipanon Benjawan Chamroenwit Malita Sanganurak Surakit Nathisuwan Usa Chaikledkaew Junporn Kongwatcharapong |
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Sayamon Sukkha |
title |
Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
title_short |
Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
title_full |
Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
title_fullStr |
Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
title_full_unstemmed |
Quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in Thailand |
title_sort |
quality assessment and cost saving of renal dosing recommendation by clinical pharmacists at medical wards in thailand |
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2020 |
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https://repository.li.mahidol.ac.th/handle/123456789/54561 |
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