Systematic review of statistical methods for safety data in malaria chemoprevention in pregnancy trials

• Main Authors: Noel Patson, Mavuto Mukaka, Kennedy N. Otwombe, Lawrence Kazembe, Don P. Mathanga, Victor Mwapasa, Alinune N. Kabaghe, Marinus J.C. Eijkemans, Miriam K. Laufer, Tobias Chirwa
• Other Authors: University of Namibia
• Format: Article
• Published: 2020
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/54575
• Institution: Mahidol University

© 2020 The Author(s). Background: Drug safety assessments in clinical trials present unique analytical challenges. Some of these include adjusting for individual follow-up time, repeated measurements of multiple outcomes and missing data among others. Furthermore, pre-specifying appropriate analysis...