Clinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: A randomized controlled trial

• Main Authors: Tospon Lertwattanachai, Preecha Montakantikul, Viratch Tangsujaritvijit, Pitsucha Sanguanwit, Jetjamnong Sueajai, Saranya Auparakkitanon, Pitchaya Dilokpattanamongkol
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/54603
• Institution: Mahidol University

© 2020 The Author(s). Background: Appropriate antimicrobial dosing is challenging because of changes in pharmacokinetics (PK) parameters and an increase in multidrug-resistant (MDR) organisms in critically ill patients. This study aimed to evaluate the effects of an empirical therapy of high-dose ve...