High glucose induces phosphorylation and oxidation of mitochondrial proteins in renal tubular cells: A proteomics approach

• Main Authors: Siripat Aluksanasuwan, Sirikanya Plumworasawat, Thanyalak Malaitad, Sakdithep Chaiyarit, Visith Thongboonkerd
• Other Authors: Faculty of Medicine, Siriraj Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/54718
• Institution: Mahidol University

© 2020, The Author(s). Mitochondrial dysfunction has been thought to play roles in the pathogenesis of diabetic nephropathy (DN). However, precise mechanisms underlying mitochondrial dysfunction in DN remained unclear. Herein, mitochondria were isolated from renal tubular cells after exposure to nor...