Endoplasmic reticulum stress, unfolded protein response and autophagy contribute to resistance to glucocorticoid treatment in human acute lymphoblastic leukaemia cells

Endoplasmic reticulum stress, unfolded protein response and autophagy contribute to resistance to glucocorticoid treatment in human acute lymphoblastic leukaemia cells

© 2020 Spandidos Publications. All rights reserved. Acute lymphoblastic leukaemia (ALL) is the most frequent childhood cancer and, although it is highly treatable, resistance to therapy, toxicity and side effects remain challenging. The synthetic glucocorticoid (GC) dexamethasone (Dex) is commonly u...

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Bibliographic Details
Main Authors: Sangkab Sudsaward, Sasiprapa Khunchai, Chutamas Thepmalee, Aisha Othman, Thawornchai Limjindaporn, Pa Thai Yenchitsomanus, Luciano Mutti, Marija Krstic-Demonacos, Constantinos Demonacos
Other Authors: Faculty of Biology, Medicine and Health
Format: Article
Published: 2020
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/57683
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/57683

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