SWATH-Proteomics of Ibrutinib's Action in Myeloid Leukemia Initiating Mutated G-CSFR Signaling

• Main Authors: Pankaj Dwivedi, Somchai Chutipongtanate, David E. Muench, Mohammad Azam, Harry Leighton Grimes, Kenneth D. Greis
• Other Authors: Cincinnati Children's Hospital Medical Center
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/57758
• Institution: Mahidol University

© 2020 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Purpose: To evaluate cellular protein changes in response to treatment with an approved drug, ibrutinib, in cells expressing normal or mutated granulocyte-colony stimulating factor receptor (G-CSFR). G-CSFR mutations are associated with some he...