Investigation on the epoxidation of piperitenone, and structure-activity relationships of piperitenone oxide for differentiation-inducing activity

• Main Authors: Ryohei Sato, Azusa Sasaki, Yuko Mori, Mio Komai, Shogo Kamo, Mai Onuki, Takafumi Seki, Zen Kawabe, Shu Miyajima, Shusuke Tomoshige, Tsuneomi Kawasaki, Shuichi Sato, Takako Nakamura, Nakao Kubo, Seiji Takeda, Shuichi Date, Shigehisa Okamoto, Panida Boonyaritthongchai, Krit Thirapanmethee, Mullika Traidej Chomnawang, Bhanubong Bongcheewin, Thuy Linh Nguyen, Huong Lan Thi Nguyen, Huong Thi Le, Yasushi Nakamura, Kouji Kuramochi
• Other Authors: Hanoi Medical University
• Format: Article
• Published: 2020
• Subjects: Chemical Engineering; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/57798
• Institution: Mahidol University

© 2020 by Japan Oil Chemists’ Society. Piperitenone oxide, a major chemical constituent of the essential oil of spearmint, Mentha spicata, induces differentiation in human colon cancer RCM-1 cells. In this study, piperitenone oxide and trans-piperitenone dioxide were prepared as racemic forms by epo...