Tilapia lake virus (TiLV): Genomic epidemiology and its early origin

© 2020 Blackwell Verlag GmbH Tilapia lake virus (TiLV) is an emerging virus that is rapidly spreading across the world. Over the past 6 years (2014–2020), TiLV outbreaks had been reported in at least 16 countries, spanning three continents, including Asia, Africa, and America. Despite its enormous e...

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Main Authors: Yuttapong Thawornwattana, Ha Thanh Dong, Kornsunee Phiwsaiya, Pakkakul Sangsuriya, Saengchan Senapin, Pakorn Aiewsakun
Other Authors: Suan Sunandha Rajabhat University
Format: Article
Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/57985
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spelling th-mahidol.579852020-08-25T19:00:03Z Tilapia lake virus (TiLV): Genomic epidemiology and its early origin Yuttapong Thawornwattana Ha Thanh Dong Kornsunee Phiwsaiya Pakkakul Sangsuriya Saengchan Senapin Pakorn Aiewsakun Suan Sunandha Rajabhat University Mahidol University Thailand National Center for Genetic Engineering and Biotechnology Immunology and Microbiology Veterinary © 2020 Blackwell Verlag GmbH Tilapia lake virus (TiLV) is an emerging virus that is rapidly spreading across the world. Over the past 6 years (2014–2020), TiLV outbreaks had been reported in at least 16 countries, spanning three continents, including Asia, Africa, and America. Despite its enormous economic impact, its origin, evolution and epidemiology are still largely poorly characterized. Here, we report eight TiLV whole-genome sequences from Thailand sampled between 2014 and 2019. Together with publicly available sequences from various regions of the world, we estimated the origin of TiLV to be between 2003 and 2009, 5–10 years before the first report of the virus in Israel in 2014. Our analyses consistently showed that TiLV started to spread in 2000s, and reached its peak in 2014–2016, matching well with the timing of its first report. From 2016 onwards, the global TiLV population declined steadily. This could be a result of herd immunity building up in the fish population, and/or a reflection of a better awareness of the virus coupled with a better and more cautious protocol of Tilapia importation. Despite the fact that we included all publicly available sequences, our analyses revealed long unsampled histories of TiLVs in many countries, especially towards its basal diversification. This result highlights the lack and the need for systematic surveillance of TiLV in fish. 2020-08-25T10:13:03Z 2020-08-25T10:13:03Z 2020-01-01 Article Transboundary and Emerging Diseases. (2020) 10.1111/tbed.13693 18651682 18651674 2-s2.0-85087451832 https://repository.li.mahidol.ac.th/handle/123456789/57985 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85087451832&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Immunology and Microbiology
Veterinary
spellingShingle Immunology and Microbiology
Veterinary
Yuttapong Thawornwattana
Ha Thanh Dong
Kornsunee Phiwsaiya
Pakkakul Sangsuriya
Saengchan Senapin
Pakorn Aiewsakun
Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
description © 2020 Blackwell Verlag GmbH Tilapia lake virus (TiLV) is an emerging virus that is rapidly spreading across the world. Over the past 6 years (2014–2020), TiLV outbreaks had been reported in at least 16 countries, spanning three continents, including Asia, Africa, and America. Despite its enormous economic impact, its origin, evolution and epidemiology are still largely poorly characterized. Here, we report eight TiLV whole-genome sequences from Thailand sampled between 2014 and 2019. Together with publicly available sequences from various regions of the world, we estimated the origin of TiLV to be between 2003 and 2009, 5–10 years before the first report of the virus in Israel in 2014. Our analyses consistently showed that TiLV started to spread in 2000s, and reached its peak in 2014–2016, matching well with the timing of its first report. From 2016 onwards, the global TiLV population declined steadily. This could be a result of herd immunity building up in the fish population, and/or a reflection of a better awareness of the virus coupled with a better and more cautious protocol of Tilapia importation. Despite the fact that we included all publicly available sequences, our analyses revealed long unsampled histories of TiLVs in many countries, especially towards its basal diversification. This result highlights the lack and the need for systematic surveillance of TiLV in fish.
author2 Suan Sunandha Rajabhat University
author_facet Suan Sunandha Rajabhat University
Yuttapong Thawornwattana
Ha Thanh Dong
Kornsunee Phiwsaiya
Pakkakul Sangsuriya
Saengchan Senapin
Pakorn Aiewsakun
format Article
author Yuttapong Thawornwattana
Ha Thanh Dong
Kornsunee Phiwsaiya
Pakkakul Sangsuriya
Saengchan Senapin
Pakorn Aiewsakun
author_sort Yuttapong Thawornwattana
title Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
title_short Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
title_full Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
title_fullStr Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
title_full_unstemmed Tilapia lake virus (TiLV): Genomic epidemiology and its early origin
title_sort tilapia lake virus (tilv): genomic epidemiology and its early origin
publishDate 2020
url https://repository.li.mahidol.ac.th/handle/123456789/57985
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