Study protocol for a randomised controlled trial evaluating the effects of the orexin receptor antagonist suvorexant on sleep architecture and delirium in the intensive care unit

• Main Authors: Omid Azimaraghi, Maximilian Hammer, Peter Santer, Katharina Platzbecker, Friederike C. Althoff, Maria Patrocinio, Stephanie D. Grabitz, Karuna Wongtangman, Sandra Rumyantsev, Xinling Xu, Maximilian S. Schaefer, Patrick M. Fuller, Balachundhar Subramaniam, Matthias Eikermann
• Other Authors: Beth Israel Deaconess Medical Center
• Format: Article
• Published: 2020
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/58061
• Institution: Mahidol University

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. Introduction Insomnia frequently occurs in patients admitted to an intensive care unit (ICU). Sleep-promoting agents may reduce rapid eye movement sleep and h...