Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand
© 2020 The Authors Objectives: Malaria cross-sectional surveys are rarely conducted in very low transmission settings. This study aimed to determine the prevalence and risk factors of Plasmodium infection in a near-elimination setting in southern Thailand. Methods: Two cross-sectional surveys were c...
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th-mahidol.580712020-08-25T17:29:30Z Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand Shoichi Shimizu Sadudee Chotirat Nichakan Dokkulab Isarachai Hongchad Kessuda Khowsroy Kirakorn Kiattibutr Nongnuj Maneechai Khajohnpong Manopwisedjaroen Pattamaporn Petchvijit Kanit Phumchuea Nattawan Rachaphaew Piyarat Sripoorote Chayanut Suansomjit Waraporn Thongyod Amnat Khamsiriwatchara Saranath Lawpoolsri Borimas Hanboonkunupakarn Jetsumon Sattabongkot Wang Nguitragool Mahidol University Medicine © 2020 The Authors Objectives: Malaria cross-sectional surveys are rarely conducted in very low transmission settings. This study aimed to determine the prevalence and risk factors of Plasmodium infection in a near-elimination setting in southern Thailand. Methods: Two cross-sectional surveys were conducted in areas of active transmission in the Surat Thani province of Thailand in January and May 2019. PCR was used to detect Plasmodium infection. Results: The prevalence of Plasmodium blood infection was 0.45% and 0.61% in January and May 2019, respectively. The major parasite species was Plasmodium falciparum in January and Plasmodium vivax in May. Unexpectedly, Plasmodium knowlesi infections were also detected. Most infections, including those of Plasmodium knowlesi, were asymptomatic. Being male and staying outdoors at night-time were the only significant identified risk factors. Of people infected in January 28.0% were positive in May for the same parasite species, suggesting persistent asymptomatic infections. Conclusions: Despite the very low incidence rate in Surat Thani, most malaria infections were asymptomatic. Outdoor mosquito biting at night-time is likely an important mode of malaria transmission. Unexpectedly, asymptomatic Plasmodium knowlesi infection was found, confirming previous reports of such infection in mainland Southeast Asia. 2020-08-25T10:29:30Z 2020-08-25T10:29:30Z 2020-07-01 Article International Journal of Infectious Diseases. Vol.96, (2020), 445-451 10.1016/j.ijid.2020.05.022 18783511 12019712 2-s2.0-85085552340 https://repository.li.mahidol.ac.th/handle/123456789/58071 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85085552340&origin=inward |
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Medicine Shoichi Shimizu Sadudee Chotirat Nichakan Dokkulab Isarachai Hongchad Kessuda Khowsroy Kirakorn Kiattibutr Nongnuj Maneechai Khajohnpong Manopwisedjaroen Pattamaporn Petchvijit Kanit Phumchuea Nattawan Rachaphaew Piyarat Sripoorote Chayanut Suansomjit Waraporn Thongyod Amnat Khamsiriwatchara Saranath Lawpoolsri Borimas Hanboonkunupakarn Jetsumon Sattabongkot Wang Nguitragool Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
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© 2020 The Authors Objectives: Malaria cross-sectional surveys are rarely conducted in very low transmission settings. This study aimed to determine the prevalence and risk factors of Plasmodium infection in a near-elimination setting in southern Thailand. Methods: Two cross-sectional surveys were conducted in areas of active transmission in the Surat Thani province of Thailand in January and May 2019. PCR was used to detect Plasmodium infection. Results: The prevalence of Plasmodium blood infection was 0.45% and 0.61% in January and May 2019, respectively. The major parasite species was Plasmodium falciparum in January and Plasmodium vivax in May. Unexpectedly, Plasmodium knowlesi infections were also detected. Most infections, including those of Plasmodium knowlesi, were asymptomatic. Being male and staying outdoors at night-time were the only significant identified risk factors. Of people infected in January 28.0% were positive in May for the same parasite species, suggesting persistent asymptomatic infections. Conclusions: Despite the very low incidence rate in Surat Thani, most malaria infections were asymptomatic. Outdoor mosquito biting at night-time is likely an important mode of malaria transmission. Unexpectedly, asymptomatic Plasmodium knowlesi infection was found, confirming previous reports of such infection in mainland Southeast Asia. |
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Mahidol University |
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Mahidol University Shoichi Shimizu Sadudee Chotirat Nichakan Dokkulab Isarachai Hongchad Kessuda Khowsroy Kirakorn Kiattibutr Nongnuj Maneechai Khajohnpong Manopwisedjaroen Pattamaporn Petchvijit Kanit Phumchuea Nattawan Rachaphaew Piyarat Sripoorote Chayanut Suansomjit Waraporn Thongyod Amnat Khamsiriwatchara Saranath Lawpoolsri Borimas Hanboonkunupakarn Jetsumon Sattabongkot Wang Nguitragool |
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Shoichi Shimizu Sadudee Chotirat Nichakan Dokkulab Isarachai Hongchad Kessuda Khowsroy Kirakorn Kiattibutr Nongnuj Maneechai Khajohnpong Manopwisedjaroen Pattamaporn Petchvijit Kanit Phumchuea Nattawan Rachaphaew Piyarat Sripoorote Chayanut Suansomjit Waraporn Thongyod Amnat Khamsiriwatchara Saranath Lawpoolsri Borimas Hanboonkunupakarn Jetsumon Sattabongkot Wang Nguitragool |
author_sort |
Shoichi Shimizu |
title |
Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
title_short |
Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
title_full |
Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
title_fullStr |
Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
title_full_unstemmed |
Malaria cross-sectional surveys identified asymptomatic infections of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in Surat Thani, a southern province of Thailand |
title_sort |
malaria cross-sectional surveys identified asymptomatic infections of plasmodium falciparum, plasmodium vivax and plasmodium knowlesi in surat thani, a southern province of thailand |
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2020 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/58071 |
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1763488693669068800 |