Development of a Cell-Based Assay for Identifying K<inf>Ca</inf>3.1 Inhibitors Using Intestinal Epithelial Cell Lines

• Main Authors: Chanon Jakakul, Phongthon Kanjanasirirat, Chatchai Muanprasat
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/58989
• Institution: Mahidol University

© Society for Laboratory Automation and Screening 2020. Inhibition of the KCa3.1 potassium channel has therapeutic potential in a variety of human diseases, including inflammation-associated disorders and cancers. However, KCa3.1 inhibitors with high therapeutic promise are currently not available....