From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma

© 2020 Purpose: To describe the transition from conventional angle surgery (CAS), trabeculotomy with rigid probe or goniotomy, to 360-degree trabeculotomy assisted with microcatheter (MCT). Design: Retrospective comparative interventional case series. Methods: Review of consecutive children with gla...

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Main Authors: Osvaldo Berger, Jibran Mohamed-Noriega, Sancy Low, Moritz C. Daniel, Sakaorat Petchyim, Maria Papadopoulos, John Brookes
Other Authors: Universität Freiburg im Breisgau
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Published: 2020
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/59143
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spelling th-mahidol.591432020-10-05T12:38:20Z From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma Osvaldo Berger Jibran Mohamed-Noriega Sancy Low Moritz C. Daniel Sakaorat Petchyim Maria Papadopoulos John Brookes Universität Freiburg im Breisgau Universidad Autónoma de Nuevo León Moorfields Eye Hospital NHS Foundation Trust UCL Institute of Ophthalmology Faculty of Medicine, Siriraj Hospital, Mahidol University St Thomas' Hospital Medicine © 2020 Purpose: To describe the transition from conventional angle surgery (CAS), trabeculotomy with rigid probe or goniotomy, to 360-degree trabeculotomy assisted with microcatheter (MCT). Design: Retrospective comparative interventional case series. Methods: Review of consecutive children with glaucoma undergoing angle surgery, including cases with previous surgery, from January 2012 until March 2018 at Moorfields Eye Hospital. Main outcome measure was success rate, defined as intraocular pressure (IOP) ≤21 mm Hg with a minimum of 20% of IOP reduction and no further glaucoma surgery (complete success: without the need of glaucoma drops; qualified success: drops were needed to keep the IOP under control). Results: Among the 106 eyes (77 patients) included were 54 MCT and 52 CAS eyes. At last visit, after a single surgery, qualified success was 85% (46 eyes) in MCT and 37% (19 eyes) in CAS. Complete success was 69% (37 cases) in MCT and 23% (12 cases) in CAS. The mean (95% confidence interval) change in axial length after surgery was −0.03 mm (−0.34 to 0.40) for MCT and +1.35 mm (−0.64 to 1.62) for CAS (P < .001). The percentage of IOP reduction was 52.1% in MCT and 45.5% in CAS (P = .1616). Further glaucoma surgery was required in 5.5% (3) in MCT and 63.4% (33) in CAS. At 1 year, 94.3% of MCT cases achieved qualified success compared to 34.6% of CAS (P < .0001). No significant complications were found on either group. Conclusion: MCT achieved better results with significantly lower reoperation rates. The transition from CAS to MCT can be easily achieved, even in difficult cases or those previously operated. 2020-10-05T05:38:20Z 2020-10-05T05:38:20Z 2020-11-01 Article American Journal of Ophthalmology. Vol.219, (2020), 77-86 10.1016/j.ajo.2020.06.017 18791891 00029394 2-s2.0-85090188398 https://repository.li.mahidol.ac.th/handle/123456789/59143 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85090188398&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Osvaldo Berger
Jibran Mohamed-Noriega
Sancy Low
Moritz C. Daniel
Sakaorat Petchyim
Maria Papadopoulos
John Brookes
From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
description © 2020 Purpose: To describe the transition from conventional angle surgery (CAS), trabeculotomy with rigid probe or goniotomy, to 360-degree trabeculotomy assisted with microcatheter (MCT). Design: Retrospective comparative interventional case series. Methods: Review of consecutive children with glaucoma undergoing angle surgery, including cases with previous surgery, from January 2012 until March 2018 at Moorfields Eye Hospital. Main outcome measure was success rate, defined as intraocular pressure (IOP) ≤21 mm Hg with a minimum of 20% of IOP reduction and no further glaucoma surgery (complete success: without the need of glaucoma drops; qualified success: drops were needed to keep the IOP under control). Results: Among the 106 eyes (77 patients) included were 54 MCT and 52 CAS eyes. At last visit, after a single surgery, qualified success was 85% (46 eyes) in MCT and 37% (19 eyes) in CAS. Complete success was 69% (37 cases) in MCT and 23% (12 cases) in CAS. The mean (95% confidence interval) change in axial length after surgery was −0.03 mm (−0.34 to 0.40) for MCT and +1.35 mm (−0.64 to 1.62) for CAS (P < .001). The percentage of IOP reduction was 52.1% in MCT and 45.5% in CAS (P = .1616). Further glaucoma surgery was required in 5.5% (3) in MCT and 63.4% (33) in CAS. At 1 year, 94.3% of MCT cases achieved qualified success compared to 34.6% of CAS (P < .0001). No significant complications were found on either group. Conclusion: MCT achieved better results with significantly lower reoperation rates. The transition from CAS to MCT can be easily achieved, even in difficult cases or those previously operated.
author2 Universität Freiburg im Breisgau
author_facet Universität Freiburg im Breisgau
Osvaldo Berger
Jibran Mohamed-Noriega
Sancy Low
Moritz C. Daniel
Sakaorat Petchyim
Maria Papadopoulos
John Brookes
format Article
author Osvaldo Berger
Jibran Mohamed-Noriega
Sancy Low
Moritz C. Daniel
Sakaorat Petchyim
Maria Papadopoulos
John Brookes
author_sort Osvaldo Berger
title From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
title_short From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
title_full From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
title_fullStr From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
title_full_unstemmed From Conventional Angle Surgery to 360-Degree Trabeculotomy in Pediatric Glaucoma
title_sort from conventional angle surgery to 360-degree trabeculotomy in pediatric glaucoma
publishDate 2020
url https://repository.li.mahidol.ac.th/handle/123456789/59143
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