A DNA repair player, ring finger protein 43, relieves etoposide-induced topoisomerase II poisoning

• Main Authors: Tassanee Lerksuthirat, Rakkreat Wikiniyadhanee, Wasana Stitchantrakul, Sermsiri Chitphuk, Nauljun Stansook, Nut Pipatpanyanugoon, Siwanon Jirawatnotai, Donniphat Dejsuphong
• Other Authors: Faculty of Medicine, Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/59858
• Institution: Mahidol University

© 2020 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd Ring finger protein 43 (RNF43) is an E3 ubiquitin ligase which is well-known for its role in negative regulation of the Wnt-signaling pathway. However, the function in DNA double-strand break repairs has not been in...