Exploring the factors underlying remyelination arrest by studying the post-transcriptional regulatory mechanisms of cystatin F gene

• Main Authors: Jiayi Li, Wilaiwan Wisessmith Durose, Junko Ito, Akiyoshi Kakita, Yohei Iguchi, Masahisa Katsuno, Kazuo Kunisawa, Takeshi Shimizu, Kazuhiro Ikenaka
• Other Authors: Nagoya University Graduate School of Medicine
• Format: Article
• Published: 2020
• Subjects: Biochemistry, Genetics and Molecular Biology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/59906
• Institution: Mahidol University

© 2020 International Society for Neurochemistry Remyelination plays an important role in determining the fate of demyelinating disorders. However, it is arrested during chronic disease states. Cystatin F, a papain-like lysosomal cysteine proteinase inhibitor, is a crucial regulator of demyelination...