Cell-Mediated Immunity to plasmodium VIVAX infection
Joint International Tropical Medicine Meeting 2004: Ambassador Hotel, Thailand 29 November-1 December 2004: abstract. Bangkok: Faculty of Tropical Medicine, Mahidol University; 2004. p.201.
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2016
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th-mahidol.633762021-08-30T22:42:20Z Cell-Mediated Immunity to plasmodium VIVAX infection Kulachart Jangpatarapongsa Jeeraphat Sirichaisinthop Jetsumon Sattabongkot Sornchai Looareesuwan ศรชัย หลูอารีย์สุวรรณ Marita Troye-Blomberg Rachanee Udomsangpetch Mahidol University. Faculty of Tropical Medicine. Department of Clinical Tropical Medicine Malaria Plasmodium VIVAX Joint International Tropical Medicine Meeting 2004: Ambassador Hotel, Thailand 29 November-1 December 2004: abstract. Bangkok: Faculty of Tropical Medicine, Mahidol University; 2004. p.201. Immunity induced by P. vivax during acute infection leads to memory T cells recruitment of which will be activated during subsequent infection. This study therefore aims to verify the level of memory T cells during acute and convalescent periods. Memory T cells are recognized by the surface molecules CD45RO+ CD27+ as an early stage and CD27- as a mature stage. The results showed significant [P<0.01] increase of mean percentage of CD4+ memory T cells during acute infection when compared with those either from healthy donors and immune villagers. The P. vivax-induced memory T cells were maintained at high level until 60 days post treatment. The mean percentage of CD8+ memory T cells was also significantly higher during acute infection until 60 days post treatment. Interestingly, the CD8+ memory T cells was stably maintained at high level among the non-acute malaria immune villagers in contrast to the low level CD4+ memory T cells in the same immune villager group. These results suggest that memory T cells particularly CD8+ phenotype-play role in the development of naturally acquired protection against P. vivax infection. The ongoing study will investigate further whether or not the protection is mediated by the memory T cells of ab-phenotype 2016-02-05T02:54:38Z 2021-08-30T15:42:20Z 2016-02-05T02:54:38Z 2021-08-30T15:42:20Z 2016-02-05 2004 Proceeding Poster https://repository.li.mahidol.ac.th/handle/123456789/63376 eng Mahidol University |
| institution |
Mahidol University |
| building |
Mahidol University Library |
| continent |
Asia |
| country |
Thailand Thailand |
| content_provider |
Mahidol University Library |
| collection |
Mahidol University Institutional Repository |
| language |
English |
| topic |
Malaria Plasmodium VIVAX |
| spellingShingle |
Malaria Plasmodium VIVAX Kulachart Jangpatarapongsa Jeeraphat Sirichaisinthop Jetsumon Sattabongkot Sornchai Looareesuwan ศรชัย หลูอารีย์สุวรรณ Marita Troye-Blomberg Rachanee Udomsangpetch Cell-Mediated Immunity to plasmodium VIVAX infection |
| description |
Joint International Tropical Medicine Meeting 2004: Ambassador Hotel, Thailand 29 November-1 December 2004: abstract. Bangkok: Faculty of Tropical Medicine, Mahidol University; 2004. p.201. |
| author2 |
Mahidol University. Faculty of Tropical Medicine. Department of Clinical Tropical Medicine |
| author_facet |
Mahidol University. Faculty of Tropical Medicine. Department of Clinical Tropical Medicine Kulachart Jangpatarapongsa Jeeraphat Sirichaisinthop Jetsumon Sattabongkot Sornchai Looareesuwan ศรชัย หลูอารีย์สุวรรณ Marita Troye-Blomberg Rachanee Udomsangpetch |
| format |
Proceeding Poster |
| author |
Kulachart Jangpatarapongsa Jeeraphat Sirichaisinthop Jetsumon Sattabongkot Sornchai Looareesuwan ศรชัย หลูอารีย์สุวรรณ Marita Troye-Blomberg Rachanee Udomsangpetch |
| author_sort |
Kulachart Jangpatarapongsa |
| title |
Cell-Mediated Immunity to plasmodium VIVAX infection |
| title_short |
Cell-Mediated Immunity to plasmodium VIVAX infection |
| title_full |
Cell-Mediated Immunity to plasmodium VIVAX infection |
| title_fullStr |
Cell-Mediated Immunity to plasmodium VIVAX infection |
| title_full_unstemmed |
Cell-Mediated Immunity to plasmodium VIVAX infection |
| title_sort |
cell-mediated immunity to plasmodium vivax infection |
| publishDate |
2016 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/63376 |
| _version_ |
1763496061106651136 |