Systemic gene silencing from oral uptake of dsRNA in Litopenaeus vannamei requires both clathrin-mediated endocytosis and LvSID-1

• Main Authors: Kamonwan Maruekawong, Orathai Namlamoon, Pongsopee Attasart
• Other Authors: Institute of Molecular Biosciences, Mahidol University
• Format: Article
• Published: 2022
• Subjects: Agricultural and Biological Sciences
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/73079
• Institution: Mahidol University

RNA interference (RNAi) is a powerful technique that has been widely applied to inhibit both DNA and RNA viruses in shrimp. To accomplish RNAi in shrimp, dsRNA is often delivered by direct injection or feeding, although the latter method has a much lower efficacy. Therefore, understanding the molecu...