Cellular localization of nucleolin determines the prognosis in cancers: a meta-analysis

• Main Authors: Supaporn Yangngam, Jaturawitt Prasopsiri, Phimmada Hatthakarnkul, Suyanee Thongchot, Peti Thuwajit, Pa thai Yenchitsomanus, Joanne Edwards, Chanitra Thuwajit
• Other Authors: Siriraj Hospital
• Format: Review
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/73469
• Institution: Mahidol University

Nucleolin (NCL) is a multifunctional protein expressed in the nucleus, cytoplasm, and cell membrane. Overexpression of NCL has a controversial role as a poor prognostic marker in cancers. In this study, a meta-analysis was performed to evaluate the prognostic value of NCL in different subcellular lo...