High-throughput RNA sequencing transcriptome analysis of ABC-DLBCL reveals several tumor evasion strategies

• Main Authors: Juana Serrano López, Carla Jiménez-Jiménez, Somchai Chutipongtanate, Josefina Serrano, Marta Rodríguez-Moreno, Álvaro Jiménez, Yesenia Jiménez, Sara G. Pedrero, Daniel Laínez, Juan Manuel Alonso-Domínguez, Pilar Llamas Sillero, Miguel Ángel Piris, Joaquín Sánchez-García
• Other Authors: Ramathibodi Hospital
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/73505
• Institution: Mahidol University

Activated B-cell (ABC) lymphoma, a distinct molecular entity within diffuse large B-cell lymphoma (DLBCL), remains highly incurable, showing a worse response to standard immunochemotherapy. The discouraging results obtained in several clinical trials using proteasome inhibitors, tyrosine kinase inhi...