Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products
In this work, we present for the first time, a simplified fabrication of a laminated paper-based analytical device (LPAD) with a free-mobile app, Palette Cam, for image analysis. A filter paper is cut in a rectangular shape (9 × 3 cm) and placed between a top laminating sheet with punched holes and...
Saved in:
Main Authors: | , , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
2022
|
Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/73699 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Mahidol University |
id |
th-mahidol.73699 |
---|---|
record_format |
dspace |
spelling |
th-mahidol.736992022-08-04T10:51:29Z Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products Nakarin Noirahaeng Kanchana Uraisin Panwadee Wattanasin Phoonthawee Saetear Mahidol University Prince of Songkla University Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs.) Chemistry In this work, we present for the first time, a simplified fabrication of a laminated paper-based analytical device (LPAD) with a free-mobile app, Palette Cam, for image analysis. A filter paper is cut in a rectangular shape (9 × 3 cm) and placed between a top laminating sheet with punched holes and a bottom laminating sheet. The holes allow accessibility of liquid on the paper. Thermal lamination is then employed to complete the fabrication of LPAD. Our simplified design reduces a tedious alignment of small pieces of paper to the holes. We demonstrated the LPAD with an analysis of salicylic acid in pharmaceutical products. Each 4 μL of ferric reagent and sample was dispensed on the LPAD. Smartphone was used to capture images. The RGB (red green blue) color intensity from the Palette Cam was converted into a logarithm color ratio. Our LPAD is simplified, cost-effective and able to be a portable device. Graphical abstract: [Figure not available: see fulltext.] 2022-08-04T03:51:29Z 2022-08-04T03:51:29Z 2022-03-01 Article Analytical Sciences. Vol.38, No.3 (2022), 533-540 10.2116/analsci.21P231 13482246 09106340 2-s2.0-85127408629 https://repository.li.mahidol.ac.th/handle/123456789/73699 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85127408629&origin=inward |
institution |
Mahidol University |
building |
Mahidol University Library |
continent |
Asia |
country |
Thailand Thailand |
content_provider |
Mahidol University Library |
collection |
Mahidol University Institutional Repository |
topic |
Chemistry |
spellingShingle |
Chemistry Nakarin Noirahaeng Kanchana Uraisin Panwadee Wattanasin Phoonthawee Saetear Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
description |
In this work, we present for the first time, a simplified fabrication of a laminated paper-based analytical device (LPAD) with a free-mobile app, Palette Cam, for image analysis. A filter paper is cut in a rectangular shape (9 × 3 cm) and placed between a top laminating sheet with punched holes and a bottom laminating sheet. The holes allow accessibility of liquid on the paper. Thermal lamination is then employed to complete the fabrication of LPAD. Our simplified design reduces a tedious alignment of small pieces of paper to the holes. We demonstrated the LPAD with an analysis of salicylic acid in pharmaceutical products. Each 4 μL of ferric reagent and sample was dispensed on the LPAD. Smartphone was used to capture images. The RGB (red green blue) color intensity from the Palette Cam was converted into a logarithm color ratio. Our LPAD is simplified, cost-effective and able to be a portable device. Graphical abstract: [Figure not available: see fulltext.] |
author2 |
Mahidol University |
author_facet |
Mahidol University Nakarin Noirahaeng Kanchana Uraisin Panwadee Wattanasin Phoonthawee Saetear |
format |
Article |
author |
Nakarin Noirahaeng Kanchana Uraisin Panwadee Wattanasin Phoonthawee Saetear |
author_sort |
Nakarin Noirahaeng |
title |
Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
title_short |
Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
title_full |
Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
title_fullStr |
Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
title_full_unstemmed |
Simplified fabrication of laminated paper-based analytical device (LPAD) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
title_sort |
simplified fabrication of laminated paper-based analytical device (lpad) with color-palette mobile app for analysis of salicylic acid in pharmaceutical products |
publishDate |
2022 |
url |
https://repository.li.mahidol.ac.th/handle/123456789/73699 |
_version_ |
1763487706104463360 |