Molecular detection and speciation of pathogenic Leptospira spp. in blood from patients with culture-negative leptospirosis

• Main Authors: Siriphan Boonsilp, Janjira Thaipadungpanit, จันทร์จิรา ไทยผดุงพานิช, Premjit Amornchai, เปรมจิตต์ อมรชัย, Vanaporn Wuthiekanun, Wirongrong Chierakul, Direk Limmathurotsakul, ดิเรก ลิ้มมธุรสกุล, Day, Nicholas P., Peacock, Sharon J.
• Format: Article
• Language: English
• Published: 2012
• Subjects: Bacterial typing techniques; DNA, bacterial; Leptospira; Prospective studies; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/740
• Institution: Mahidol University

BACKGROUND: Pathogenic Leptospira spp. present in the blood of patients with leptospirosis during the first week of symptoms can be detected using culture or PCR. A proportion of patients who are positive by PCR are negative by culture. Leptospira spp. are fastidious bacteria, and we hypothesize...