COVID-19 Breakthrough Infection after Inactivated Vaccine Induced Robust Antibody Responses and Cross-Neutralization of SARS-CoV-2 Variants, but Less Immunity against Omicron

• Main Authors: Nungruthai Suntronwong, Ritthideach Yorsaeng, Jiratchaya Puenpa, Chompoonut Auphimai, Thanunrat Thongmee, Preeyaporn Vichaiwattana, Sitthichai Kanokudom, Thaneeya Duangchinda, Warangkana Chantima, Pattarakul Pakchotanon, Suvichada Assawakosri, Pornjarim Nilyanimit, Sirapa Klinfueng, Lakkhana Wongsrisang, Donchida Srimuan, Thaksaporn Thatsanatorn, Natthinee Sudhinaraset, Nasamon Wanlapakorn, Yong Poovorawan
• Other Authors: Siriraj Hospital
• Format: Article
• Published: 2022
• Subjects: Immunology and Microbiology; Medicine; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/74145
• Institution: Mahidol University

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and the waning of immunity in vaccinated individuals is resulting in increased numbers of SARS-CoV-2 breakthrough infections. This study investigated binding antibody responses and neutralizing activities against...