The autophagy-resistant Mycobacterium tuberculosis Beijing strain upregulates KatG to evade starvation-induced autophagic restriction

The autophagy-resistant Mycobacterium tuberculosis Beijing strain upregulates KatG to evade starvation-induced autophagic restriction

Mycobacterium tuberculosis utilizes several mechanisms to block phagosome-lysosome fusion to evade host cell restriction. However, induction of host cell autophagy by starvation was shown to overcome this block, resulting in enhanced lysosomal delivery to mycobacterial phagosomes and the killing of...

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Bibliographic Details
Main Authors: Tegar Adriansyah Putra Siregar, Pinidphon Prombutara, Phongthon Kanjanasirirat, Nawapol Kunkaew, Alisa Tubsuwan, Atsadang Boonmee, Tanapat Palaga, Tanawadee Khumpanied, Suparerk Borwornpinyo, Angkana Chaiprasert, Pongsak Utaisincharoen, Marisa Ponpuak
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
Subjects:
Immunology and Microbiology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/74191
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/74191

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