Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent
A 16-year-old Thai girl developed right facial palsy, a lower motor neuron lesion, and numbness 3 h after receiving the first dose of the BNT162b2 mRNA vaccine. Neurological examination showed the involvement of the right cranial nerves (CN) V, VII, IX, and X. Electrophysiological tests revealed the...
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th-mahidol.741952022-08-04T11:49:32Z Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent Pimchanok Kulsirichawaroj Oranee Sanmaneechai Orasri Wittawatmongkol Kulkanya Chokephaibulkit Siriraj Hospital Immunology and Microbiology Medicine Pharmacology, Toxicology and Pharmaceutics A 16-year-old Thai girl developed right facial palsy, a lower motor neuron lesion, and numbness 3 h after receiving the first dose of the BNT162b2 mRNA vaccine. Neurological examination showed the involvement of the right cranial nerves (CN) V, VII, IX, and X. Electrophysiological tests revealed the absence of an F wave response, suggesting a proximal demyelinating process. Magnetic resonance imaging of the brain demonstrated abnormal enhancement of the right CN VII. The cerebrospinal fluid profile on day 7 after the onset of symptoms was normal. The patient was diagnosed with polyneuritis cranialis, a rare variant of Guillain-Barre syndrome. She was successfully treated with intravenous immunoglobulin therapy. 2022-08-04T04:10:41Z 2022-08-04T04:10:41Z 2022-01-01 Article Vaccines. Vol.10, No.1 (2022) 10.3390/vaccines10010134 2076393X 2-s2.0-85123244583 https://repository.li.mahidol.ac.th/handle/123456789/74195 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85123244583&origin=inward |
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Immunology and Microbiology Medicine Pharmacology, Toxicology and Pharmaceutics Pimchanok Kulsirichawaroj Oranee Sanmaneechai Orasri Wittawatmongkol Kulkanya Chokephaibulkit Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
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A 16-year-old Thai girl developed right facial palsy, a lower motor neuron lesion, and numbness 3 h after receiving the first dose of the BNT162b2 mRNA vaccine. Neurological examination showed the involvement of the right cranial nerves (CN) V, VII, IX, and X. Electrophysiological tests revealed the absence of an F wave response, suggesting a proximal demyelinating process. Magnetic resonance imaging of the brain demonstrated abnormal enhancement of the right CN VII. The cerebrospinal fluid profile on day 7 after the onset of symptoms was normal. The patient was diagnosed with polyneuritis cranialis, a rare variant of Guillain-Barre syndrome. She was successfully treated with intravenous immunoglobulin therapy. |
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Siriraj Hospital |
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Siriraj Hospital Pimchanok Kulsirichawaroj Oranee Sanmaneechai Orasri Wittawatmongkol Kulkanya Chokephaibulkit |
format |
Article |
author |
Pimchanok Kulsirichawaroj Oranee Sanmaneechai Orasri Wittawatmongkol Kulkanya Chokephaibulkit |
author_sort |
Pimchanok Kulsirichawaroj |
title |
Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
title_short |
Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
title_full |
Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
title_fullStr |
Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
title_full_unstemmed |
Polyneuritis Cranialis Associated with BNT162b2 mRNA COVID-19 Vaccine in a Healthy Adolescent |
title_sort |
polyneuritis cranialis associated with bnt162b2 mrna covid-19 vaccine in a healthy adolescent |
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2022 |
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https://repository.li.mahidol.ac.th/handle/123456789/74195 |
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1763497050698153984 |