Diagnostic accuracy of interferon-gamma release assays for diagnosis of smear-negative pulmonary tuberculosis: a systematic review and meta-analysis

• Main Authors: Tananchai Petnak, Dararat Eksombatchai, Supavit Chesdachai, Ploypin Lertjitbanjong, Pahnwat Taweesedt, Angsupat Pornchai, Charat Thongprayoon, Larry J. Prokop, Zhen Wang
• Other Authors: Faculty of Medicine Ramathibodi Hospital, Mahidol University
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/74255
• Institution: Mahidol University

Introduction: The diagnosis of smear-negative pulmonary tuberculosis (SNPTB) is challenging. Interferon gamma-release assays (IGRAs) may be helpful in early diagnosis among these patients resulting in prompt treatment and favorable outcomes. Methods: We performed a comprehensive search from each dat...