Long-term Safety and Immunogenicity of a Tetravalent Dengue Vaccine Candidate in Children and Adults: A Randomized, Placebo-Controlled, Phase 2 Study

• Main Authors: Chukiat Sirivichayakul, Elizabeth A. Barranco-Santana, Inés Esquilín Rivera, Jennifer Kilbury, Marsha Raanan, Astrid Borkowski, Athanasia Papadimitriou, Derek Wallace
• Other Authors: Faculty of Tropical Medicine, Mahidol University
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/74605
• Institution: Mahidol University

Background: We report long-term safety and immunogenicity of Takeda's tetravalent dengue vaccine candidate (TAK-003) in healthy children and adults living in dengue-endemic areas in Puerto Rico, Columbia, Singapore, and Thailand. Methods: In part 1 of this phase 2, randomized, placebo-controlle...