Evolution of HLA-B Pharmacogenomics and the Importance of PGx Data Integration in Health Care System: A 10 Years Retrospective Study in Thailand

Background: The HLA-B is the most polymorphic gene, play a crucial role in drug-induced hypersensitivity reactions. There is a lot of evidence associating several risk alleles to life-threatening adverse drug reactions, and a few of them have been approved as valid biomarkers for predicting life-thr...

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Main Authors: Napatrupron Koomdee, Chiraphat Kloypan, Pimonpan Jinda, Jiratha Rachanakul, Thawinee Jantararoungtong, Rattanaporn Sukprasong, Santirhat Prommas, Nutthan Nuntharadthanaphong, Apichaya Puangpetch, Maliheh Ershadian, Shobana John, Mohitosh Biswas, Chonlaphat Sukasem
Other Authors: Ramathibodi Hospital
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/74618
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Institution: Mahidol University