Lung- and Diaphragm-Protective Ventilation by Titrating Inspiratory Support to Diaphragm Effort: A Randomized Clinical Trial

• Main Authors: Heder J. de Vries, Annemijn H. Jonkman, Harm J. de Grooth, Jan Willem Duitman, Armand R.J. Girbes, Coen A.C. Ottenheijm, Marcus J. Schultz, Peter M. van de Ven, Yingrui Zhang, Angelique M.E. de Man, Pieter R. Tuinman, Leo M.A. Heunks
• Other Authors: Amsterdam Cardiovascular Sciences
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/74841
• Institution: Mahidol University

OBJECTIVES: Lung- and diaphragm-protective ventilation is a novel concept that aims to limit the detrimental effects of mechanical ventilation on the diaphragm while remaining within limits of lung-protective ventilation. The premise is that low breathing effort under mechanical ventilation causes d...