Efficacy of a standardized Centella asiatica (ECa 233) extract against allodynia in a mouse model of temporomandibular osteoarthritis

• Main Authors: Nattapon Rotpenpian, Aree Wanasuntronwong, Sompol Tapechum, Chit Care, Atitaya Roumwong, Kanokwan Tilokskulchai, Mayuree H. Tantisira, Narawut Pakaprot
• Other Authors: Siriraj Hospital
• Format: Article
• Published: 2022
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/75493
• Institution: Mahidol University

Prolonged inflammation causing tissue injury can induce chronic pain hypersensitivity (allodynia and hyperalgesia). Osteoarthritis of the temporomandibular joint (TMJ-OA) is a common cause of chronic allodynia encountered in dental practice, but many currently available treatments induce intolerable...