Caffeine induces g0/g1 cell cycle arrest and inhibits migration through Integrin αv, β3, and FAK/AKT/c-MYC signaling pathway

• Main Authors: Pichitchai Meisaprow, Nithikoon Aksorn, Chanida Vinayanuwattikun, Pithi Chanvorachote, Monruedee Sukprasansap
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemistry; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/75891
• Institution: Mahidol University

Lung cancer is recognized as a major cause of mortality worldwide owing to its metastatic activity. Given the lack of solid information regarding the possible effects of caffeine, one of the most consumed natural psychoactive substances, on molecular signaling pathways implicated in the aggressive b...