EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma

EMP2 induces cytostasis and apoptosis via the TGFβ/SMAD/SP1 axis and recruitment of P2RX7 in urinary bladder urothelial carcinoma

Purpose: Urinary bladder urothelial carcinoma (UBUC) is a common malignant disease, and its high recurrence rates impose a heavy clinical burden. The objective of this study was to identify signaling pathways downstream of epithelial membrane protein 2 (EMP2), which induces cytostasis and apoptosis...

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Main Authors: Chien Feng Li, Ti Chun Chan, Cheng Tang Pan, Pichpisith Pierre Vejvisithsakul, Jia Chen Lai, Szu Yu Chen, Ya Wen Hsu, Meng Shin Shiao, Yow Ling Shiue
Other Authors: Chi Mei Medical Center
Format: Article
Published: 2022
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76010
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/76010

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