Human hazard assessment using drosophila wing spot test as an alternative in vivo model for genotoxicity testing—A review

• Main Authors: Pornsiri Pitchakarn, Woorawee Inthachat, Jirarat Karinchai, Piya Temviriyanukul
• Other Authors: Faculty of Medicine, Chiang Mai University
• Format: Review
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Computer Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76043
• Institution: Mahidol University

Genomic instability, one of cancer’s hallmarks, is induced by genotoxins from endogenous and exogenous sources, including reactive oxygen species (ROS), diet, and environmental pollutants. A sensitive in vivo genotoxicity test is required for the identification of human hazards to reduce the potenti...