Feasibility of chitosan-based nanoparticles approach for intranasal immunisation of live attenuated Japanese encephalitis vaccine

Intranasal (IN) administration, a non-invasive route, is explored to overcome the limitations of conventional subcutaneous (SC) injection for Japanese encephalitis (JE) immunisation. Mucoadhesive nanoparticles (NPs) are recognised for the benefits they offer via IN delivery, such as extended retenti...

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Main Authors: Ekachai Dumkliang, Boonnada Pamornpathomkul, Prasopchai Patrojanasophon, Tanasait Ngawhirunpat, Theerasak Rojanarata, Sutee Yoksan, Praneet Opanasopit
Other Authors: Chulabhorn Research Institute
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76099
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Institution: Mahidol University