Five-(Tetradecyloxy)-2-furoic acid alleviates cholangiocarcinoma growth by inhibition of cell-cycle progression and induction of apoptosis

• Main Authors: Piyanard Boonnate, Ryusho Kariya, Paksiree Saranaruk, Ubon Cha'on, Kanlayanee Sawanyawisuth, Sarawut Jitrapakdee, Seiji Okada, Kulthida Vaeteewoottacharn
• Other Authors: Graduate School of Medical Sciences
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76120
• Institution: Mahidol University

Background/Aim: Cholangiocarcinoma (CCA), a biliary cancer, is a health problem worldwide. The major problem in CCA treatment presents limited options. To date, targeting cancer metabolism is a promising anti-cancer strategy. To elucidate the functional importance of lipid metabolism in CCA, de novo...