Gambogic Acid Inhibits Wnt/β-catenin Signaling and Induces ER Stress-Mediated Apoptosis in Human Cholangiocarcinoma

Gambogic Acid Inhibits Wnt/β-catenin Signaling and Induces ER Stress-Mediated Apoptosis in Human Cholangiocarcinoma

Objective: Gambogic acid (GA) has been reported to induce apoptosis in cholangiocarcinoma (CCA) cell lines. However, the molecular mechanisms underlying its anti-cancer activity remain poorly understood. This study was aimed to investigate GA's effect on human CCA cell lines, KKU-M213 and HuCCA...

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Bibliographic Details
Main Authors: Kanoknetr Suksen, Keatdamrong Janpipatkul, Somrudee Reabroi, Natthinee Anantachoke, Vichai Reutrakul, Arthit Chairoungdua, Natthakan Thongon, Kanit Bhukhai
Other Authors: Vajira Hospital
Format: Article
Published: 2022
Subjects:
Biochemistry, Genetics and Molecular Biology
Medicine
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76147
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/76147

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