Protective effect of lusianthridin on hemin-induced low-density lipoprotein oxidation

• Main Authors: Su Wutyi Thant, Noppawan Phumala Morales, Visarut Buranasudja, Boonchoo Sritularak, Rataya Luechapudiporn
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Pharmacology, Toxicology and Pharmaceutics
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76150
• Institution: Mahidol University

Oxidation of low-density lipoprotein (LDL) plays a crucial role in the pathogenesis of atherosclerosis. Hemin (iron (III)-protoporphyrin IX) is a degradation product of hemoglobin that can be found in thalassemia patients. Hemin is a strong oxidant that can cause LDL oxidation and contributes to ath...