Protective effects of a lutein ester prodrug, lutein diglutaric acid, against h<inf>2</inf> o<inf>2</inf>-induced oxidative stress in human retinal pigment epithelial cells

• Main Authors: Chawanphat Muangnoi, Rianthong Phumsuay, Nattapong Jongjitphisut, Pasin Waikasikorn, Monsin Sangsawat, Paitoon Rashatasakhon, Luminita Paraoan, Pornchai Rojsitthisak
• Other Authors: Chulalongkorn University
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Computer Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76192
• Institution: Mahidol University

Oxidative stress-induced cell damage and death of the retinal pigmented epithelium (RPE), a polarized monolayer that maintains retinal health and homeostasis, lead to the development of age-related macular degeneration (AMD). Several studies show that the naturally occurring antioxidant Lutein (Lut)...