High-efficacy α,β-dehydromonacolin s improves hepatic steatosis and suppresses gluconeogenesis pathway in high-fat diet-induced obese rats

High-efficacy α,β-dehydromonacolin s improves hepatic steatosis and suppresses gluconeogenesis pathway in high-fat diet-induced obese rats

Isolated α,β-dehydromonacolin S (C5) from soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 was recently shown to exhibit an inhibitory effect against 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity in vitro. In this study, we investigated the effects of C5 on lipid-lowering,...

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Main Authors: Jutatip Kaewmalee, Atcharaporn Ontawong, Acharaporn Duangjai, Chittreeya Tansakul, Vatcharin Rukachaisirikul, Chatchai Muanprasat, Chutima Srimaroeng
Other Authors: University of Phayao
Format: Article
Published: 2022
Subjects:
Biochemistry, Genetics and Molecular Biology
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/76221
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/76221

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