What can urinary exosomes tell us?
Exosomes are involved in a wide variety of biochemical processes in human body homeostasis. Exosomes also provide important information regarding communications among several organ systems. Additionally, they can serve as molecular vehicles to deliver drugs. Therefore, exosomes have received wide at...
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th-mahidol.762362022-08-04T18:22:45Z What can urinary exosomes tell us? Rui Vitorino Rita Ferreira Sofia Guedes Francisco Amado Visith Thongboonkerd LAQV-REQUIMTE Universidade de Aveiro Faculdade de Medicina da Universidade do Porto (FMUP) Faculty of Medicine Siriraj Hospital, Mahidol University Biochemistry, Genetics and Molecular Biology Neuroscience Pharmacology, Toxicology and Pharmaceutics Exosomes are involved in a wide variety of biochemical processes in human body homeostasis. Exosomes also provide important information regarding communications among several organ systems. Additionally, they can serve as molecular vehicles to deliver drugs. Therefore, exosomes have received wide attention in current biomedical research for unraveling pathogenic mechanisms of diseases, searching for novel biomarkers, and discovering new drugs. This paper reviews and discusses the significance of urinary exosomes for a better understanding of human disease pathophysiology and their potential use as therapeutic targets. Isolation methods of exosomes and the latest technological advances are also discussed. Furthermore, novel urinary exosomal biomarkers are highlighted with special emphasis on their clinical applicability (particularly sensitivity, specificity, reliability, and other aspects). Finally, future trends for this field are analyzed and our perspectives are provided. 2022-08-04T08:10:49Z 2022-08-04T08:10:49Z 2021-04-01 Review Cellular and Molecular Life Sciences. Vol.78, No.7 (2021), 3265-3283 10.1007/s00018-020-03739-w 14209071 1420682X 2-s2.0-85099855239 https://repository.li.mahidol.ac.th/handle/123456789/76236 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85099855239&origin=inward |
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Biochemistry, Genetics and Molecular Biology Neuroscience Pharmacology, Toxicology and Pharmaceutics Rui Vitorino Rita Ferreira Sofia Guedes Francisco Amado Visith Thongboonkerd What can urinary exosomes tell us? |
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Exosomes are involved in a wide variety of biochemical processes in human body homeostasis. Exosomes also provide important information regarding communications among several organ systems. Additionally, they can serve as molecular vehicles to deliver drugs. Therefore, exosomes have received wide attention in current biomedical research for unraveling pathogenic mechanisms of diseases, searching for novel biomarkers, and discovering new drugs. This paper reviews and discusses the significance of urinary exosomes for a better understanding of human disease pathophysiology and their potential use as therapeutic targets. Isolation methods of exosomes and the latest technological advances are also discussed. Furthermore, novel urinary exosomal biomarkers are highlighted with special emphasis on their clinical applicability (particularly sensitivity, specificity, reliability, and other aspects). Finally, future trends for this field are analyzed and our perspectives are provided. |
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LAQV-REQUIMTE |
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LAQV-REQUIMTE Rui Vitorino Rita Ferreira Sofia Guedes Francisco Amado Visith Thongboonkerd |
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Review |
author |
Rui Vitorino Rita Ferreira Sofia Guedes Francisco Amado Visith Thongboonkerd |
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Rui Vitorino |
title |
What can urinary exosomes tell us? |
title_short |
What can urinary exosomes tell us? |
title_full |
What can urinary exosomes tell us? |
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What can urinary exosomes tell us? |
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What can urinary exosomes tell us? |
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what can urinary exosomes tell us? |
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2022 |
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https://repository.li.mahidol.ac.th/handle/123456789/76236 |
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