Protective effect of mediterranean-type glucose-6-phosphate dehydrogenase deficiency against plasmodium vivax malaria

• Main Authors: Ghulam R. Awab, Fahima Aaram, Natsuda Jamornthanyawat, Kanokon Suwannasin, Watcharee Pagornrat, James A. Watson, Charles J. Woodrow, Arjen M. Dondorp, Nicholas P.J. Day, Mallika Imwong, Nicholas J. White
• Other Authors: Mahidol University
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76290

X-linked glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzymopathy. The severe Mediterranean variant (G6PD Med) found across Europe and Asia is thought to confer protection against malaria, but its effect is unclear. We fitted a Bayesian statistical model to observed G...